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Patients with a Migraine AttackA migraine attack does not affect the pharmacokinetics of rizatriptan.

There are no adequate and well-controlled studies in pregnant womenthereforerizatriptan should be used during pregnancy only if the potential benefit justifies the potential risk to the foetus.

Prolonged use of any painkiller for headaches can make them worseIf this situation is experienced or suspectedmedical advice should be obtained and treatment should be discontinuedThe diagnosis of MOH should be suspected in patients who have frequent or daily headaches despiteor because ofthe regular use of headache medications.

Angio-oedemae.gfacial oedematongue swelling and pharyngeal oedemamay occur in patients treated with triptanssuch as rizatriptanIf angio-oedema of the tongue or pharynx occursthe patient should be placed under medical supervision until the symptoms have resolvedTreatment should promptly be discontinued and replaced by an agent belonging to another class of drugs.

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concurrent administration of mao inhibitors or use of rizact md within 2 weeks of discontinuation of mao inhibitor therapy is contraindicated.

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