When sentiment turned against lariam in 2008, its manufacturer, hoffmann la roche ceased marketing it in the us and now the words lariam and malaria draw no search results on its u.
This appears to be the only clinically relevant interaction of this kind with Lariammefloquinealthough theoreticallycoadministration of other drugs known to alter cardiac conductioneganti-arrhythmic or beta-adrenergic blocking agentscalcium channel blockersantihistamines or H 1blocking agentstricyclic antidepressants and phenothiazinesmight also contribute to a prolongation of the QTc intervalThere are no data that conclusively establish whether the concomitant administration of mefloquine and the above listed agents has an effect on cardiac function.
Please read the following section if you are taking the tablets to help prevent you from catching malaria.
Lariammefloquineis indicated for the treatment of mild to moderate acute malaria caused by mefloquine-susceptible strains of Pfalciparumboth chloroquine-susceptible and resistant strainsor by Plasmodium vivaxThere are insufficient clinical data to document the effect of mefloquine in malaria caused by Povale or Pmalariae.
Below is a text only representation of the Patient Information LeafletThe original can be viewed in PDF format using the link above.
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see the end of this medication guide for a complete list of ingredients in lariam.