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Danazol can harm an unborn baby or cause vaginal birth defects in a newborn female infantDo not use if you are pregnant.

Acne or other skin problemsincreased sweatingincreased hair growth or hair lossbreast changesdecreased amount of semen released during sexhoarse or deepened voicesore throatflushingwarmthrednessor tingly feelingchanges in your menstrual periodsunusual vaginal bleeding or spottingvaginal drynessdiscomfortor itching.

Danazol should be given as a continuous coursedosage being adjusted according to the severity of the condition and the patient’s responseA reduction in dosage once a satisfactory response has been achieved may prove possibleIn fertile femalesDanazol should be started during menstruationpreferably on the first dayto avoid exposing a pregnancy to its possible effectsWhere doubt existsappropriate checks should be made to exclude pregnancy before starting medicationFemales of child-bearing age should employ non-hormonal contraception throughout the course of treatment.

Datafrom two case-control epidemiological studieswere pooled to examine the relationship between endometriosisendometriosis treatments and ovarian cancerThese preliminary results suggest that the use of danazol might increase the baseline risk of ovarian cancer inpatients treated for endometriosis.

Datafrom two case-control epidemiological studieswere pooled to examine the relationship between endometriosisendometriosis treatments and ovarian cancerThese preliminary results suggest that the use of danazol might increase the baseline risk of ovarian cancer inpatients treated for endometriosis.

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