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Sinemet cr is contraindicated in patients with known hypersensitivity to any component of this drug, and in patients with narrow-angle glaucoma.

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Abnormal uncontrolled movements including muscle twitching or spasmswhich may or may not resemble your Parkinson’s symptoms dizzinesslight-headedness when standing quickly feeling sicknauseavomitingloss of appetite discolouration of urinesweat and/or saliva dream abnormalities sleepiness or sudden onset of sleep slow movements twitching or spasm of the eyelids hair loss diarrhoea.

The management of NMS should include1intensive symptomatic treatment and medical monitoring and 2treatment of any concomitant serious medical problems for which specific treatments are availableDopamine agonistssuch as bromocriptineand muscle relaxantssuch as dantroleneare often used in the treatment of NMShowevertheir effectiveness has not been demonstrated in controlled studies.

If it is almost time for your next doseskip the dose you missed and take your next dose when you are meant toOtherwisetake it as soon as you rememberand then go back to taking your tablet(sas you would normally.

For patients receiving MAO inhibitorsType A or Bsee CONTRAINDICATIONSConcomitant therapy with selegiline and carbidopa levodopa may be associated with severe orthostatic hypotension not attributable to carbidopa levodopa alonesee CONTRAINDICATIONS

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sinemet still makes him sleepy, but he finds he can let it wear off in the afternoon and he needs no more until breakfast the next day.

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